About Central Pharmacy

Central Pharmacy is a trusted Health & Wellness destination in Durham, NC, where personal care, convenience, and dependable service come together to support the needs of the community. Located at 2609 N Duke St Building 100, Ste 103, this pharmacy is dedicated to making everyday health management easier and more reassuring for customers who want quick access to the medications and services they rely on. With a strong 4.70 out of 5 rating from 46 reviews, Central Pharmacy has built a reputation for quality care and customer satisfaction, reflecting the confidence that local residents place in its service. What sets Central Pharmacy apart is its commitment to flexibility and accessibility. Customers can take advantage of kerbside pickup, delivery, and on-site services, making it simple to get prescriptions and wellness support in the way that best fits their schedule. Whether you need a fast stop during a busy day or prefer the convenience of having items brought to you, the pharmacy is designed to make the process smooth and efficient. For those planning a quick visit, Central Pharmacy helps save time without sacrificing the attentive service that makes a real difference in health care. Accessibility is also a clear priority, with wheelchair-accessible parking and a wheelchair-accessible entrance ensuring that more members of the community can visit comfortably and confidently. The pharmacy also offers medication disposal, adding an important layer of safety and responsibility for households looking to manage unused or expired medicines properly. With multiple payment options accepted, including cheques, debit cards, NFC mobile payments, and credit cards, Central Pharmacy makes checkout straightforward and convenient. For questions or assistance, customers can call +1 919-220-5121 and connect with a pharmacy that values reliability, ease, and the well-being of every person it serves.

Last updated: Jul 30, 2026

Business Hours

Closed · Monday 9 am–5:30 pm
Sunday Closed
Monday 9 am–5:30 pm
Tuesday 9 am–5:30 pm
Wednesday 9 am–5:30 pm
Thursday 9 am–5:30 pm
Friday 9 am–5:30 pm
Saturday 9 am–12 pm

Customer Reviews

4.70
Based on 46 reviews
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Tyler Hart

I am the owner of Eno River Orthodontics and call in a few rare prescriptions. These guys are on the ball. They are very helpful and have compounded topical anesthetic for me without any trouble. I highly recommend them. Even better is that Central Pharmacy is locally owned and operated!

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Ashley Hogan

Every single one here is fantastic! I'm so grateful for this pharmacy. They truly care about people and helping meet your pharmaceutical needs. They even go into detail regarding the purpose of the medication you need, how it works, how it can cause side effects etc....I feel more at peace talking with them sometimes than the Doctor that prescribed the …

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Lynn Hayes

I discovered Central Pharmacy when I was looking for a vaccine. I sent a text through their website and didn’t expect to hear anything back, but I received quick response and was put on a waitlist right away and was able to snag an appointment that was open. The process was seamless and the staff is so nice, such a …

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Aimee Toney

Excellent pharmacy with wonderful staff. Always friendly and happy to help answer questions and address concerns. Refills are easy to request and they're super responsive.

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Winston Mangum

I switched to Central Pharmacy when another drug store decided to retire. I hope Central Pharmacy doesn’t decide to retire or close any time soon. They are very efficient, friendly and professional. I can’t praise them enough. They are much better than ANY big pharmacy. Keep up the high standards.

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Barbara Atkinson

This is, by far, the very best pharmacy I have ever used. Every employee goes out of their way to provide exceptional, caring and professional service. They treat everyone with respect and courtesy and if there ever is a problem they graciously fix it right away. If I could give them more than five stars I would!

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Nancy Zarrello

I have been a customer of Central Compounding Pharmacy for just a short time, but I have been extremely pleased with their service, especially their staff. Recently I had a problem getting a prescription renewed by my doctor. The staff at the pharmacy contacted the doctor several times on my behalf and kept me updated each time. They were sympathetic, …

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Jessica Nuccio

I've been using this pharmacy for many years and tell everyone I can to go here instead of the nightmare large chain pharmacies. The staff are so nice and remember all of their customers. They are great about problem solving and communicating. Never a long wait and they have an easy to use website for refills. They even deliver if …

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Fran James

Since Upchurch Drugs closed down I have been getting prescriptions from Central Pharmacy. Jennifer and her staff are amazing! Everyone is so nice and welcoming from the minute you walk in the door until you leave. Love that it's family owned. Gotta shop local! Customer for life!

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Jessica

The only pharmacy in the area who will provide a compounded medication to me without jumping through a million hoops or judgment. Friendly staff, very responsive and respectful and it is refreshing to do business with actual human beings and not AI or automated phone trees.

People Also Ask

Where is Central Pharmacy located?
Central Pharmacy is located at 2609 N Duke St Building 100, Ste 103, Durham, NC 27704, United States. You can get directions here.
What is Central Pharmacy rated?
Central Pharmacy has a rating of 4.70 out of 5 stars based on 46 customer reviews.
What are Central Pharmacy's hours?
Central Pharmacy's hours vary by day. Please check the Business Hours section above for the full weekly schedule.
How do I contact Central Pharmacy?
You can reach Central Pharmacy by phone at +1 919-220-5121.
What type of business is Central Pharmacy?
Central Pharmacy is a health & wellness business located in Durham, NC 27704. <!-- VOILA_REWRITTEN --> Central Pharmacy is a trusted Health & Wellness destination in Durham, NC, where personal care, convenience, and dependable service come together to support the needs of the …